Extracellular Alpha-Synuclein Promotes a Neuroinhibitory Secretory Phenotype in Astrocytes

Multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) are α-synucleinopathies that exhibit widespread astrogliosis as a component of the neuroinflammatory response. Munc18, a protein critical to vesicle exocytosis, was previously found to strongly mark morphologically activated astrocyte...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Life
المؤلفون الرئيسيون:	Bruno Di Marco Vieira, Rowan A. W. Radford, Junna Hayashi, Emma D. Eaton, Ben Greenaway, Mark Jambas, Eugen B. Petcu, Roger S. Chung, Dean L. Pountney
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2020-09-01
الموضوعات:	astrocytes astrogliosis MSA DLB Munc18
الوصول للمادة أونلاين:	https://www.mdpi.com/2075-1729/10/9/183