Changes E3 ubiquitin protein ligase 1 gene mRNA expression correlated with IgA1 glycosylation in patients with IgA nephropathy

Background: Recent genomewide association study suggested that the top single-nucleotide polymorphism, rs978056, in HECW1 gene (which encodes HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1) associated with the levels of galactose-deficient IgA1 (Gd-IgA1) in IgA nephropathy (IgAN). H...

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Bibliographic Details

Published in:	Renal Failure
Main Authors:	Youxia Liu, Jie Zheng, Junya Jia, Hongfen Li, Shuiyi Hu, Yujia Lin, Tiekun Yan
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2019-01-01
Subjects:	galactose-deficient iga1 hecw1 mrna level rs978056 iga nephropathy
Online Access:	http://dx.doi.org/10.1080/0886022X.2019.1605295