Liposomal factor VIII as an efficient pharmaceutical system for the treatment of hemophilia

Objective(s): Currently, the most important treatment approach for hemophilia type A is recombinant Factor VIII. However, due to its low retention time in the blood, the patients usually need successive injections. In addition, neutralization of injected proteins by antibodies complicates treatment....

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Bibliographic Details

Published in:	Iranian Journal of Basic Medical Sciences
Main Authors:	Maryam Karimi, Seyed Mahdi Rezayat, Seyed Alireza Mortazavi, Azadeh Haeri, Mahmoud Reza Jaafari
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2024-06-01
Subjects:	antihemophilic factor hemophilia a pegylated liposomes recombinant fviii haemophilia therapy
Online Access:	https://ijbms.mums.ac.ir/article_23891_294e60660171fdf99ae5e7519656baf7.pdf