The Progress and Challenges of Implementing HLA Molecular Matching in Clinical Practice

HLA molecular matching in solid organ transplantation in the form of eplets, solvent-accessible amino acids or PIRCHE-II has been proposed as a more granular method than HLA matching on the antigen level. While many studies have shown the association between molecular mismatches and de novo donor-sp...

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Bibliographic Details

Published in:	Transplant International
Main Authors:	Suzanne Bezstarosti, Sebastiaan Heidt
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Subjects:	HLA eplet kidney transplantation molecular mismatch organ allocation
Online Access:	https://www.frontierspartnerships.org/articles/10.3389/ti.2025.14716/full