Development of a humanized mouse model with functional human materno-fetal interface immunity

Materno-fetal immunity possesses specialized characteristics to ensure pathogen clearance while maintaining tolerance to the semiallogeneic fetus. Most of our understanding on human materno-fetal immunity is based on conventional rodent models that may not precisely represent human immunological pro...

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Bibliographic Details

Published in:	JCI Insight
Main Authors:	Shuai Dong, Cong Fu, Chang Shu, Min Xie, Yan Li, Jun Zou, Yi-Zi Meng, Peng Xu, Yan-Hong Shan, Hui-Min Tian, Jin He, Yong-Guang Yang, Zheng Hu
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2024-10-01
Subjects:	Immunology Reproductive biology
Online Access:	https://doi.org/10.1172/jci.insight.176527