CATATOnia treatment with transcranial direct current electrostimulation: protocol of a randomised, double-blind, placebo-controlled bicentric superiority study (CATATOES)

Abstract Background Catatonia is a severe psychomotor syndrome with high morbidity and mortality. Lorazepam and electroconvulsive therapy (ECT) are the main recommended treatments. Lorazepam-resistant catatonia accounts for about 30% of cases, particularly in neurodevelopmental disorders. ECT is cru...

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Published in:	BMC Psychiatry
Main Authors:	Mylène Moyal, David Attali, Alice Le Berre, Noomane Bouaziz, Anton Iftimovici, François Ramon, Adèle Henensal, Louise Dahan, Laetitia Canivet, Ghita Dadi, Clément Debacker, Maliesse Lui, Sylvain Charron, Anaëlle Alouit, Khaoussou Sylla, Rossella Letizia Mancusi, Thierry Gallarda, Arnaud Cachia, Martine Gavaret, Boris Chaumette, Catherine Oppenheim, Dominique Januel, Marion Plaze, Alexandre Haroche
Format:	Article
Language:	English
Published:	BMC 2025-10-01
Subjects:	Neuromodulation TDCS Catatonic syndrome EEG MRI Genetic
Online Access:	https://doi.org/10.1186/s12888-025-07266-5