Reverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulence.

Candida albicans, the major fungal pathogen of humans, causes life-threatening infections in immunocompromised individuals. Due to limited available therapy options, this can frequently lead to therapy failure and emergence of drug resistance. To improve current treatment strategies, we have combine...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS Pathogens
المؤلفون الرئيسيون: Elias Epp, Ghyslaine Vanier, Doreen Harcus, Anna Y Lee, Gregor Jansen, Michael Hallett, Don C Sheppard, David Y Thomas, Carol A Munro, Alaka Mullick, Malcolm Whiteway
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Public Library of Science (PLoS) 2010-02-01
الوصول للمادة أونلاين:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000753&type=printable