Primary Cilia in Pancreatic β- and α-Cells: Time to Revisit the Role of Insulin-Degrading Enzyme

The primary cilium is a narrow organelle located at the surface of the cell in contact with the extracellular environment. Once underappreciated, now is thought to efficiently sense external environmental cues and mediate cell-to-cell communication, because many receptors, ion channels, and signalin...

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Bibliographic Details
Published in:Frontiers in Endocrinology
Main Authors: Marta Pablos, Elena Casanueva-Álvarez, Carlos M. González-Casimiro, Beatriz Merino, Germán Perdomo, Irene Cózar-Castellano
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Subjects:
primary cilium
insulin-degrading enzyme
pancreas
β-cell
α-cell
insulin signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.922825/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.922825/full

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