Decreased Siglec-9 Expression on Natural Killer Cell Subset Associated With Persistent HBV Replication

Siglec-9 is an MHC-independent inhibitory receptor selectively expressed on CD56dim NK cells. Its role in infection diseases has not been investigated yet. Here, we studied the potential regulatory roles of NK Siglec-9 in the pathogenesis of chronic hepatitis B (CHB) infection. Flow cytometry evalua...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Di Zhao, Xuemei Jiang, Yong Xu, Huimin Yang, Dongni Gao, Xueen Li, Lifen Gao, Chunhong Ma, Xiaohong Liang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-05-01
Subjects:	chronic hepatitis B Siglec-9 NK cytokine synthesis cytotoxicity
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2018.01124/full