Transient p53 Suppression Increases Reprogramming of Human Fibroblasts without Affecting Apoptosis and DNA Damage

The discovery of human-induced pluripotent stem cells (iPSCs) has sparked great interest in the potential treatment of patients with their own in vitro differentiated cells. Recently, knockout of the Tumor Protein 53 (p53) gene was reported to facilitate reprogramming but unfortunately also led to g...

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Bibliographic Details

Published in:	Stem Cell Reports
Main Authors:	Mikkel A. Rasmussen, Bjørn Holst, Zeynep Tümer, Mads G. Johnsen, Shuling Zhou, Tina C. Stummann, Poul Hyttel, Christian Clausen
Format:	Article
Language:	English
Published:	Elsevier 2014-09-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213671114002367