Preclinical modeling of lower-grade gliomas

Models for human gliomas prove critical not only to advancing our understanding of glioma biology but also to facilitate the development of therapeutic modalities. Specifically, creating lower-grade glioma (LGG) models has been challenging, contributing to few investigations and the minimal progress...

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Bibliographic Details
Published in:Frontiers in Oncology
Main Authors: Lilly W. Tang, Arka N. Mallela, Hansen Deng, Timothy E. Richardson, Shawn L. Hervey-Jumper, Samuel K. McBrayer, Kalil G. Abdullah
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Subjects:
glioma
organoids
preclinical models
lower-grade glioma
cerebral organoids
patient-derived 3D tumor explants
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1139383/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1139383/full

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