Simvastatin, but not pravastatin, inhibits the proliferation of esophageal adenocarcinoma and squamous cell carcinoma cells: a cell-molecular study

Abstract Background and objective Long-term statin therapy has been shown to protect against several cancers, including esophageal cancer (EC). While the mechanisms underlying this effect are not clear. We investigated the effect of hydrophobic simvastatin and hydrophilic pravastatin on the prolifer...

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Bibliographic Details

Published in:	Lipids in Health and Disease
Main Authors:	Yan Chen, Li-Bin Li, Jun Zhang, Du-Peng Tang, Jing-Jing Wei, Ze-Hao Zhuang
Format:	Article
Language:	English
Published:	BMC 2018-12-01
Subjects:	Statin Esophageal squamous carcinoma cell Esophageal adenocarcinoma cell Proliferation
Online Access:	http://link.springer.com/article/10.1186/s12944-018-0946-7