Evaluation of potential of targeted sequencing through mutational signature simulation.

<h4>Background</h4>Targeted sequencing is critical in cancer diagnosis, treatment selection, and monitoring. However, the effectiveness of these methods for reflecting whole-exome sequencing (WES)-level mutational signatures remains unclear. Therefore, we addressed this issue through sim...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Keisuke Kodama, Yiwei Ling, Hiroshi Ichikawa, Toshifumi Wakai, Shujiro Okuda
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0326071