Pharmacokinetic and Pharmacodynamic Considerations of Antibiotic Use in Neonates

The selection of an appropriate dose of a given antibiotic for a neonate not only requires knowledge of the drug’s basic pharmacokinetic (PK) and pharmacodynamic (PD) properties but also the profound effects that organ development might have on the volume of distribution and clearance, both of which...

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Bibliographic Details

Published in:	Antibiotics
Main Authors:	Mario Regazzi, Alberto Berardi, Simonetta Picone, Chryssoula Tzialla
Format:	Article
Language:	English
Published:	MDPI AG 2023-12-01
Subjects:	newborns pharmacokinetics pharmacodynamics therapeutic drug monitoring model-informed precision dosing
Online Access:	https://www.mdpi.com/2079-6382/12/12/1747