Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation

Urease is a nickel-containing enzyme that is essential for the survival of several and often deadly pathogenic bacterial strains, including <i>Helicobacter pylori</i>. Notwithstanding several attempts, the development of direct urease inhibitors without side effects for the human host re...

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Bibliographic Details
Published in:Molecules
Main Authors: Matteo Masetti, Federico Falchi, Dario Gioia, Maurizio Recanatini, Stefano Ciurli, Francesco Musiani
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Subjects:
urease
<i>Helicobacter pylori</i>
virtual screening
protein tunnels
protein–protein interaction
Online Access:https://www.mdpi.com/1420-3049/25/12/2911

Internet

https://www.mdpi.com/1420-3049/25/12/2911

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