INVESTIGATION OF THE GENETIC ALTERATIONS IN CDKN2A/B AND IL7R IN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematopoietic disorder triggered by the acquisition of molecular alterations that affect thymocytes in early stages of its development. Deletions in CDKN2A/B are found in ̃65-70% of cases. However, their prognostic value is still undefined...

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Bibliographic Details

Published in:	Hematology, Transfusion and Cell Therapy
Main Authors:	RMB Lemos, ES Costa, T Ferraz, MT Schramm, MM Lins, MCN Fagundes, ALT Maciel, M Emerenciano
Format:	Article
Language:	English
Published:	Elsevier 2024-10-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2531137924009465