Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs

Anthracyclines are widely used in the treatment of many solid cancers, but their efficacy is limited by cardiotoxicity. As the number of pediatric cancer survivors continues to rise, there has been a concomitant increase in people living with anthracycline-induced cardiotoxicity. Accordingly, there...

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書誌詳細

出版年:	Antioxidants
主要な著者:	Ignacio Reinal, Imelda Ontoria-Oviedo, Marta Selva, Marilù Casini, Esteban Peiró-Molina, Carlos Fambuena-Santos, Andreu M. Climent, Julia Balaguer, Adela Cañete, Jaume Mora, Ángel Raya, Pilar Sepúlveda
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2023-07-01
主題:	iPSC-derived cardiomyocytes cardiotoxicity pediatric patients oxidative stress doxorubicin microRNA
オンライン･アクセス:	https://www.mdpi.com/2076-3921/12/7/1378