SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode

Abstract The ongoing evolution of SARS-CoV-2 into more easily transmissible and infectious variants has provided unprecedented insight into mutations enabling immune escape. Understanding how these mutations affect the dynamics of antibody-antigen interactions is crucial to the development of broadl...

Full description

Bibliographic Details

Published in:	Communications Biology
Main Authors:	Jule Goike, Ching-Lin Hsieh, Andrew P. Horton, Elizabeth C. Gardner, Ling Zhou, Foteini Bartzoka, Nianshuang Wang, Kamyab Javanmardi, Andrew Herbert, Shawn Abbassi, Xuping Xie, Hongjie Xia, Pei-Yong Shi, Rebecca Renberg, Thomas H. Segall-Shapiro, Cynthia I. Terrace, Wesley Wu, Raghav Shroff, Michelle Byrom, Andrew D. Ellington, Edward M. Marcotte, James M. Musser, Suresh V. Kuchipudi, Vivek Kapur, George Georgiou, Scott C. Weaver, John M. Dye, Daniel R. Boutz, Jason S. McLellan, Jimmy D. Gollihar
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-12-01
Online Access:	https://doi.org/10.1038/s42003-023-05649-6