High-throughput sequencing of the B-cell receptor in African Burkitt lymphoma reveals clues to pathogenesis

Abstract: Burkitt lymphoma (BL), the most common pediatric cancer in sub-Saharan Africa, is a malignancy of antigen-experienced B lymphocytes. High-throughput sequencing (HTS) of the immunoglobulin heavy (IGH) and light chain (IGK/IGL) loci was performed on genomic DNA from 51 primary BL tumors: 19...

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Bibliographic Details

Published in:	Blood Advances
Main Authors:	Katharine A. Lombardo, David G. Coffey, Alicia J. Morales, Christopher S. Carlson, Andrea M.H. Towlerton, Sarah E. Gerdts, Francis K. Nkrumah, Janet Neequaye, Robert J. Biggar, Jackson Orem, Corey Casper, Sam M. Mbulaiteye, Kishor G. Bhatia, Edus H. Warren
Format:	Article
Language:	English
Published:	Elsevier 2017-03-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2473952920301543