Gene signatures associated with prognosis and chemotherapy resistance in glioblastoma treated with temozolomide

Background: Glioblastoma (GBM) prognosis remains extremely poor despite standard treatment that includes temozolomide (TMZ) chemotherapy. To discover new GBM drug targets and biomarkers, genes signatures associated with survival and TMZ resistance in GBM patients treated with TMZ were identified.Met...

Full description

Bibliographic Details
Published in:Frontiers in Genetics
Main Authors: Tonia Carter, Robert K. Valenzuela, Srinivasulu Yerukala Sathipati, Rafael Medina-Flores
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Subjects:
chemotherapy resistance
glioblastoma
oncogene
somatic variant
temozolomide
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1320789/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1320789/full

Similar Items