Acetylation of FOXO1 is involved in cadmium-induced rat kidney injury via mediating autophagosome-lysosome fusion blockade and autophagy inhibition

Cadmium (Cd), a potentially toxic elements, has the potential to cause harm to the kidneys. Studies has demonstrated that autophagosome-lysosome fusion blockade and consequent autophagy inhibition is related to Cd-induced kidney injury. Studies indicate that acetylation of forkhead box protein O1 (F...

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Bibliographic Details

Published in:	Ecotoxicology and Environmental Safety
Main Authors:	Yingxin Ruan, Yang Xue, Pengyu Zhang, Junya Jia
Format:	Article
Language:	English
Published:	Elsevier 2024-11-01
Subjects:	Cadmium Autophagy Acetylation of FOXO1 Sirt1 Lysosome
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651324013290