Prolyl isomerase pin1 protects mice from endotoxin shock.

Prolyl isomerase Pin1 may be involved in innate immunity against microbial infection, but the mechanism how Pin1 controls the innate immunity is poorly understood.Injection of lipopolysaccharide (LPS) into the mice induces inflammatory pulmonary disorder and sometimes the serious damages lead to dea...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Hirotada Akiyama, Takuma Misawa, Masao Ono, Chiyoko Uchida, Takafumi Uchida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Online Access:http://europepmc.org/articles/PMC3033895?pdf=render