Structural investigations on the mitochondrial uncouplers niclosamide and FCCP

There has been renewed interest in using mitochondrial uncoupler compounds such as niclosamide and carbonyl cyanide p‐(trifluoromethoxy)phenylhydrazone (FCCP) for the treatment of obesity, hepatosteatosis and diseases where oxidative stress plays a role. However, both FCCP and niclosamide have undes...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:FEBS Open Bio
المؤلفون الرئيسيون: Mei Ying Ng, Zhi Jian Song, Choon Hong Tan, Marcella Bassetto, Thilo Hagen
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Wiley 2024-07-01
الموضوعات:
الوصول للمادة أونلاين:https://doi.org/10.1002/2211-5463.13817