The Effect of Simvastatin on Gut Microbiota and Lipid Metabolism in Hyperlipidemic Rats Induced by a High-Fat Diet

The objective of this study was to investigate the effects of simvastatin (SIM) on lipid metabolism disorders and gut microbiota in high-fat diet-induced hyperlipidemic rats. The obtained results revealed that feeding rats with SIM (20 mg/kg/day) significantly decreased serum lipid level and inhibit...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Frontiers in Pharmacology
المؤلفون الرئيسيون: Qing Zhang, Xiaoyun Fan, Rui Ye, Yuzhong Hu, Tingting Zheng, Rui Shi, Wenjian Cheng, Xucong Lv, Lijiao Chen, Peng Liang
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Frontiers Media S.A. 2020-04-01
الموضوعات:
الوصول للمادة أونلاين:https://www.frontiersin.org/article/10.3389/fphar.2020.00522/full