PKA and PKC Balance in Synapse Elimination during Neuromuscular Junction Development

During the development of the nervous system, synaptogenesis occurs in excess though only the appropriate connections consolidate. At the neuromuscular junction, competition between several motor nerve terminals results in the maturation of a single axon and the elimination of the others. The activi...

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Bibliographic Details

Published in:	Cells
Main Authors:	Neus Garcia, Maria A. Lanuza, Marta Tomàs, Víctor Cilleros-Mañé, Laia Just-Borràs, Maria Duran, Aleksandra Polishchuk, Josep Tomàs
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Subjects:	motor end-plate postnatal synapse elimination axonal competition acetylcholine release nicotinic acetylcholine receptor clusters protein kinases
Online Access:	https://www.mdpi.com/2073-4409/10/6/1384