Absence of diurnal variation in visceromotor response to colorectal distention in normal Long Evans rats [version 1; referees: 2 approved]

Background: Enhanced colorectal sensitivity (i.e. visceral hypersensitivity) is thought to be a pathophysiological mechanism in irritable bowel syndrome (IBS). In healthy men a circadian variation in rectal perception to colonic distention was described. Disturbed day and night rhythms, which occur...

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Bibliographic Details

Published in:	F1000Research
Main Authors:	Sara Botschuijver, Zhumei Yu, Olaf Welting, Cathy Cailotto, Andries Kalsbeek, Rene van den Wijngaard
Format:	Article
Language:	English
Published:	F1000 Research Ltd 2016-01-01
Subjects:	Colon & Rectum Gastrointestinal Physiology
Online Access:	http://f1000research.com/articles/5-98/v1