Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node

The detection of foreign antigens in vivo has relied on fluorescent conjugation or indirect read-outs such as antigen presentation. In our studies, we found that these widely used techniques had several technical limitations that have precluded a complete picture of antigen trafficking or retention...

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Bibliographic Details

Published in:	eLife
Main Authors:	Shannon M Walsh, Ryan M Sheridan, Erin D Lucas, Thu A Doan, Brian C Ware, Johnathon Schafer, Rui Fu, Matthew A Burchill, Jay R Hesselberth, Beth Ann Jiron Tamburini
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2021-04-01
Subjects:	single-cell mRNA sequencing lymph node antigen processing antigen archiving lymphatic endothelial cell dendritic cell
Online Access:	https://elifesciences.org/articles/62781