Uncovering active ingredients and mechanisms of Pholiota adiposa in the treatment of Alzheimer’s disease based on network pharmacology and bioinformatics

Abstract Pholiota adiposa is recognized for its health benefits, particularly in Alzheimer’s disease (AD), but its molecular mechanism remains elusive. Our study employs network pharmacology and machine learning to uncover its therapeutic potential. We constructed a network of AD-relevant target pro...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Ma Xiaoying, Huo Zhiming, Shi Mingwen, Wang Hong, Yang Tao, Xiao Jun, Gong Na
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-07-01
Subjects:	Alzheimer’s disease Machine learning Network pharmacology Pholiota adiposa
Online Access:	https://doi.org/10.1038/s41598-025-94861-x