Essential Role for Ethanolamine Plasmalogen Hydrolysis in Bacterial Lipopolysaccharide Priming of Macrophages for Enhanced Arachidonic Acid Release

Due to their high content in esterified arachidonic acid (AA), macrophages provide large amounts of eicosanoids during innate immune reactions. Bacterial lipopolysaccharide (LPS) is a poor trigger of AA mobilization in macrophages but does have the capacity to prime these cells for greatly increased...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Luis Gil-de-Gómez, Alma M. Astudillo, Patricia Lebrero, María A. Balboa, Jesús Balsinde
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-09-01
Subjects:	lipolysaccharide priming arachidonic acid phospholipid remodeling lipid mediators eicosanoids monocytes/macrophages
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01251/full