Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing.

The protein called p97 in mammals and Cdc48 in budding and fission yeast is a homo-hexameric, ring-shaped, ubiquitin-dependent ATPase complex involved in a range of cellular functions, including protein degradation, vesicle fusion, DNA repair, and cell division. The cdc48+ gene is essential for viab...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Irina N Marinova, Jacob Engelbrecht, Adrian Ewald, Lasse L Langholm, Christian Holmberg, Birthe B Kragelund, Colin Gordon, Olaf Nielsen, Rasmus Hartmann-Petersen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Online Access:	http://europepmc.org/articles/PMC4319823?pdf=render