stormTB: a web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments

IntroductionTuberculosis (TB) poses a significant threat to global health, with millions of new infections and approximately one million deaths annually. Various modeling efforts have emerged, offering tailored data-driven and physiologically-based solutions for novel and historical compounds. Howev...

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الحاوية / القاعدة:	Frontiers in Pharmacology
المؤلفون الرئيسيون:	Roberto Visintainer, Anna Fochesato, Daniele Boaretti, Stefano Giampiccolo, Shayne Watson, Micha Levi, Federico Reali, Luca Marchetti
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2025-01-01
الموضوعات:	physiologically based modeling pharmacokinetics pharmacodynamics ADME tuberculosis web interface
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1462193/full