Targeting metabolism and membrane: Neferine synergizes with gentamicin against Escherichia coli by disrupting FNR/ArcA-Mediated homeostasis

The escalating prevalence of antimicrobial-resistant bacteria, particularly in food and environmental settings, poses a severe global health threat. E. coli with rising resistance to gentamicin exemplifies this crisis, necessitating novel strategies to restore antibiotic efficacy. This study identif...

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Bibliographic Details

Published in:	Virulence
Main Authors:	Yasong Yan, Minghe Zhao, Hanjun Zhao, Xingyu Yan, Lingcong Kong, Hongxia Ma
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2026-06-01
Subjects:	Antibiotic resistance gentamicin Neferine FNR ArcA TCM monomer
Online Access:	https://www.tandfonline.com/doi/10.1080/21505594.2026.2690833