Casein kinase I epsilon interacts with mitochondrial proteins for the growth and survival of human ovarian cancer cells

Abstract Epithelial ovarian cancer is the leading cause of death among gynaecologic cancers in Western countries. Our studies have shown that casein kinase I‐epsilon (CKIε), a Wnt pathway protein, is significantly overexpressed in ovarian cancer tissues and is associated with poor survival. Ectopic...

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Bibliographic Details

Published in:	EMBO Molecular Medicine
Main Authors:	Noah Rodriguez, Junzheng Yang, Kathleen Hasselblatt, Shubai Liu, Yilan Zhou, Jose A. Rauh‐Hain, Shu‐Kay Ng, Pui‐Wah Choi, Wing‐Ping Fong, Nathalie Y. R. Agar, William R. Welch, Ross S. Berkowitz, Shu‐Wing Ng
Format:	Article
Language:	English
Published:	Springer Nature 2012-06-01
Subjects:	casein kinase I epsilon mitochondria ovarian cancer therapeutic target Wnt signalling
Online Access:	https://doi.org/10.1002/emmm.201101094