Exploring lipin1 as a promising therapeutic target for the treatment of Duchenne muscular dystrophy

Abstract Background Duchenne muscular dystrophy (DMD) is a progressive and devastating muscle disease, resulting from the absence of dystrophin. This leads to cell membrane instability, susceptibility to contraction-induced muscle damage, subsequent muscle degeneration, and eventually disability and...

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Bibliographic Details
Published in:Journal of Translational Medicine
Main Authors: Abdulrahman Jama, Abdullah A. Alshudukhi, Steve Burke, Lixin Dong, John Karanja Kamau, Brooklyn Morris, Ibrahim A. Alkhomsi, Brian N. Finck, Andrew Alvin Voss, Hongmei Ren
Format: Article
Language:English
Published: BMC 2024-07-01
Subjects:
lipin1
DMD
Muscular dystrophy
Dystrophin
Skeletal muscle
Therapeutic target
Online Access:https://doi.org/10.1186/s12967-024-05494-z

Internet

https://doi.org/10.1186/s12967-024-05494-z

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