Roles of PDE1 in Pathological Cardiac Remodeling and Dysfunction

Pathological cardiac hypertrophy and dysfunction is a response to various stress stimuli and can result in reduced cardiac output and heart failure. Cyclic nucleotide signaling regulates several cardiac functions including contractility, remodeling, and fibrosis. Cyclic nucleotide phosphodiesterases...

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Bibliographic Details

Published in:	Journal of Cardiovascular Development and Disease
Main Authors:	Si Chen, Walter E. Knight, Chen Yan
Format:	Article
Language:	English
Published:	MDPI AG 2018-04-01
Subjects:	phosphodiesterases (PDEs) PDE1 cyclic nucleotide cardiac hypertrophy cardiac dysfunction
Online Access:	http://www.mdpi.com/2308-3425/5/2/22