SARS-CoV-2 viral proteins trigger pain via TLR2/4-MyD88 pathway

Somatosensory disorders, especially pain, are prominent symptoms of COVID-19. Except for the viral infection process, SARS-CoV-2 viral proteins might be directly sensed by corresponding receptors, thereby triggering nociceptive signals in the dorsal root ganglion (DRG) and spinal dorsal horn (SDH)....

Full description

Bibliographic Details

Published in:	Frontiers in Molecular Neuroscience
Main Authors:	Wenliang Su, Xinrui Wang, Minghui Gu, Qiwei Zheng, Jiawen Yu, Dongliang Mu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	SARS-CoV-2 TLR2 TLR4 MyD88 pain
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2025.1163636/full