The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow

Monoclonal antibodies directed against the neuropeptide calcitonin gene-related peptide (CGRP) belong to a new generation of therapeutics that are effective in the prevention of migraine. CGRP, a potent vasodilator, is strongly implicated in the pathophysiology of migraine, but its role remains to b...

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出版年:	Cells
主要な著者:	Mária Dux, Birgit Vogler, Annette Kuhn, Kimberly D. Mackenzie, Jennifer Stratton, Karl Messlinger
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2022-05-01
主題:	fremanezumab monoclonal antibody calcitonin gene-related peptide glycerol trinitrate CGRP release meningeal blood flow
オンライン･アクセス:	https://www.mdpi.com/2073-4409/11/11/1768