Assessment of androgen receptor, IGF-IR and insulin receptor expression in male patients with severe peripheral artery disease

Background: Peripheral artery disease (PAD) of the lower limbs is a common condition that can affect quality of life. Androgen receptor (AR) can exert sex-specific effects on metabolic system, endothelial function and vascular tone. IGF-I receptor (IGF-IR) and insulin receptor (IR) may also be invol...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Michele Andreucci, Damiano Cosimo Rigiracciolo, Umberto Marcello Bracale, Nicola Ielapi, Michele Provenzano, Diletta D'Iuorno, Ashour Michael, Pasquale Mastroroberto, Giuseppe Filiberto Serraino, Marcello Maggiolini, Raffaele Serra
Format:	Article
Language:	English
Published:	Elsevier 2022-01-01
Subjects:	Peripheral artery disease IGF-I receptor Insulin receptor Androgen receptor PAD AR
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844022000445