Impact of metal oxide nanoparticles on in vitro DNA amplification

Polymerase chain reaction (PCR) is used as an in vitro model system of DNA replication to assess the genotoxicity of nanoparticles (NPs). Prior results showed that several types of NPs inhibited PCR efficiency and increased amplicon error frequency. In this study, we examined the effects of various...

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Bibliographic Details
Published in:PeerJ
Main Authors: Chun-Hui Gao, Monika Mortimer, Ming Zhang, Patricia A. Holden, Peng Cai, Shan Wu, Yuexing Xin, Yichao Wu, Qiaoyun Huang
Format: Article
Language:English
Published: PeerJ Inc. 2019-06-01
Subjects:
Nanoparticle
DNA polymerase
Metal oxides
DNA replication
Genotoxicity
Online Access:https://peerj.com/articles/7228.pdf

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https://peerj.com/articles/7228.pdf

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