Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle

BackgroundRenal cell carcinoma (RCC) is a prevalent type of malignant tumor with high morbidity and mortality. The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.MethodsThis study explored the effects of lathyrol on the proliferation of Renca mouse RC...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Shengyou Song, Yalin Song
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	lathyrol renal cell cancer TGF-β/Smad signalingsmad signal pathway cell cycle proliferation
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1629962/full