Efficacy of PRaG therapy in microsatellite-stable metastatic colorectal cancer: a comparative analysis of PD-1/PD-L1 inhibitor-based combination therapies

Abstract Background Most (95%) metastatic colorectal cancers (mCRCs) exhibit microsatellite stability (MSS) and proficiency in DNA mismatch repair (pMMR), leading to resistance to immunotherapy. To overcome this, the combination of programmed cell death protein 1 (PD-1)/programmed cell death ligand...

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出版年:	Cancer Immunology, Immunotherapy
主要な著者:	Jiabao Yang, Xiangrong Zhao, Pengfei Xing, Yuehong Kong, Meiling Xu, Liyuan Zhang
フォーマット:	論文
言語:	英語
出版事項:	Springer 2025-10-01
主題:	MSS/pMMR Colorectal cancer PD-1/PD-L1 inhibitor Radiotherapy Retrospective study
オンライン･アクセス:	https://doi.org/10.1007/s00262-025-04185-y