Editing the Melanocortin-4 Receptor Gene in Channel Catfish Using the CRISPR-Cas9 System

The melanocortin-4 receptor (MC4R) plays a critical role in homeostasis and the regulation of body weight. Polymorphisms in the <i>mc4r</i> gene have been discovered and linked to growth, carcass composition, and meat quality traits. Therefore, we used the CRISPR-Cas9 system to target th...

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Bibliographic Details

Published in:	Fishes
Main Authors:	Karim Khalil, Ahmed Elaswad, Hisham Abdelrahman, Maximillian Michel, Wenbiao Chen, Shikai Liu, Ramjie Odin, Zhi Ye, David Drescher, Khoi Vo, William S. Bugg, Guyu Qin, Yujia Yang, Nathan J. C. Backenstose, Zhanjiang Liu, Roger D. Cone, Rex Dunham
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	channel catfish gene editing CRISPR-Cas9 growth rate feed conversion ratio mutations
Online Access:	https://www.mdpi.com/2410-3888/8/2/116