The Prospects of an Active Vaccine Against Asthma Targeting IL-5

Allergen-specific T helper type 2 (Th2) responses followed by eosinophilic inflammation of the lung are important causes of allergic asthma. Interleukin-5 (IL-5) is a master regulator of eosinophil differentiation as well as activation. Blocking IL-5 using monoclonal antibodies (mAbs) against IL-5 i...

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Bibliographic Details
Published in:Frontiers in Microbiology
Main Authors: Martin F. Bachmann, Aadil El-Turabi, Antonia Fettelschoss-Gabriel, Monique Vogel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Subjects:
virus-like particle
IL-5
vaccine
asthma
cytokine
vaccination
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02522/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02522/full

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