A role for androgen receptor variant 7 in sensitivity to therapy: Involvement of IGFBP-2 and FOXA1

Prostate cancer (PCa) is one of the leading causes of cancer-related deaths in men. Localised PCa can be treated effectively, but most patients relapse/progress to more aggressive disease. One possible mechanism underlying this progression is alternative splicing of the androgen receptor, with AR va...

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Bibliographic Details
Published in:Translational Oncology
Main Authors: K.M. Biernacka, R. Barker, A. Sewell, A. Bahl, C.M. Perks
Format: Article
Language:English
Published: Elsevier 2023-08-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323000840