Proposed mechanisms of action participating in the hypoglycemic effect of the traditionally used Croton guatemalensis Lotsy and junceic acid, its main compound

Croton guatemalensis Lotsy (Euphorbiaceae) is an important traditional medicine that is used by the Cakchiquels of Guatemala to control hyperglycemia in patients with type 2 diabetes. Previous studies have shown that administration of this plant induces an acute hypoglycemic effect during fasting an...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Angelina Daniela Moreno-Vargas, Adolfo Andrade-Cetto, Fernanda Artemisa Espinoza-Hernández, Gerardo Mata-Torres
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-10-01
Subjects:	Croton guatemalensis junceic acid traditional medicine type 2 diabetes hypoglycemic hepatic glucose production inhibition
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1436927/full