Association of genetic risk of Alzheimer’s disease and cognitive function in two European populations

Abstract Although there is some evidence of an association between Alzheimer’s disease polygenic risk score (AD PRS) and cognitive function, limited validations have been performed in large populations. We investigated the relationship between AD PRS and cognitive function in the UK Biobank in over...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Biqi Wang, Lori B. Chibnik, Seung Hoan Choi, Deborah Blacker, Anita L. DeStefano, Honghuang Lin
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-02-01
Subjects:	Alzheimer’s disease Polygenic risk score Cognitive test Cohort
Online Access:	https://doi.org/10.1038/s41598-025-90277-9