Sepsis-Induced Gut Dysbiosis Mediates the Susceptibility to Sepsis-Associated Encephalopathy in Mice

ABSTRACT Sepsis-associated encephalopathy (SAE) is common in septic patients and is associated with adverse outcomes. The gut microbiota has been recognized as a key mediator of neurological disease development. However, the exact role of the gut microbiota in regulating SAE remains elusive. Here, w...

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Bibliographic Details

Published in:	mSystems
Main Authors:	Heng Fang, Yirong Wang, Jia Deng, Huidan Zhang, Qingrui Wu, Linling He, Jing Xu, Xin Shao, Xin Ouyang, Zhimei He, Qiuping Zhou, Huifang Wang, Yiyu Deng, Chunbo Chen
Format:	Article
Language:	English
Published:	American Society for Microbiology 2022-06-01
Subjects:	gut microbiota sepsis-associated encephalopathy indole-3-propionic acid microglia
Online Access:	https://journals.asm.org/doi/10.1128/msystems.01399-21