The nonlinear cysteine redox dynamics in the i-space: A proteoform-centric theory of redox regulation

The post-translational redox regulation of protein function by cysteine oxidation controls diverse biological processes, from cell division to death. However, most current site-centric paradigms fail to capture the nonlinear and emergent nature of redox regulation in proteins with multiple cysteines...

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Bibliographic Details

Published in:	Redox Biology
Main Authors:	James N. Cobley, Panagiotis N. Chatzinikolaou, Cameron A. Schmidt
Format:	Article
Language:	English
Published:	Elsevier 2025-04-01
Subjects:	Oxiforms Redox regulation I-space Nonlinear Cysteine proteoforms
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231725000369