Expression analysis of LEDGF/p75, APOBEC3G, TRIM5alpha, and tetherin in a Senegalese cohort of HIV-1-exposed seronegative individuals.

HIV-1 replication depends on a delicate balance between cellular co-factors and antiviral restriction factors. Lens epithelium-derived growth factor (LEDGF/p75) benefits HIV, whereas apolipoprotein B mRNA-editing catalytic polypeptide-like 3G (APOBEC3G), tripartite motif 5alpha (TRIM5α), and tetheri...

Full description

Bibliographic Details
Published in:PLoS ONE
Main Authors: Kim Mous, Wim Jennes, Makhtar Camara, Moussa Seydi, Géraldine Daneau, Souleymane Mboup, Luc Kestens, Xaveer Van Ostade
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Online Access:http://europepmc.org/articles/PMC3313979?pdf=render