scReQTL: an approach to correlate SNVs to gene expression from individual scRNA-seq datasets

Abstract Background Recently, pioneering expression quantitative trait loci (eQTL) studies on single cell RNA sequencing (scRNA-seq) data have revealed new and cell-specific regulatory single nucleotide variants (SNVs). Here, we present an alternative QTL-related approach applicable to transcribed S...

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Bibliographic Details

Published in:	BMC Genomics
Main Authors:	Hongyu Liu, N. M. Prashant, Liam F. Spurr, Pavlos Bousounis, Nawaf Alomran, Helen Ibeawuchi, Justin Sein, Piotr Słowiński, Krasimira Tsaneva-Atanasova, Anelia Horvath
Format:	Article
Language:	English
Published:	BMC 2021-01-01
Subjects:	eQTL, ReQTL, scReQTL, single cell VAFRNA scVAFRNA scRNA-seq SNV Genetic variation
Online Access:	https://doi.org/10.1186/s12864-020-07334-y